Multiple Cis-acting elements modulate programmed -1 ribosomal frameshifting in Pea enation mosaic virus
نویسندگان
چکیده
منابع مشابه
Multiple Cis-acting elements modulate programmed -1 ribosomal frameshifting in Pea enation mosaic virus
Programmed -1 ribosomal frameshifting (-1 PRF) is used by many positive-strand RNA viruses for translation of required products. Despite extensive studies, it remains unresolved how cis-elements just downstream of the recoding site promote a precise level of frameshifting. The Umbravirus Pea enation mosaic virus RNA2 expresses its RNA polymerase by -1 PRF of the 5'-proximal ORF (p33). Three hai...
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Programmed -1 ribosomal frameshifting (-1 PRF) has been identified as a mechanism to regulate the expression of many viral genes and some cellular genes. The slippery site of -1 PRF has been well characterized, whereas the +1 PRF signal and the mechanism involved in +1 PRF remain poorly understood. Previous study confirmed that +1 PRF is required for the synthesis of protein products in several...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2015
ISSN: 1362-4962,0305-1048
DOI: 10.1093/nar/gkv1241